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Dr. Anne Gatignol

Academic title(s): 

Professor - Department of Medicine

Dr. Anne Gatignol
Contact Information
Address: 

Lady Davis Institute for Medical Research
Jewish General Hospital
3755 Côte Ste-Catherine Road,
Montreal, Qc, H3T 1E2

Phone: 
(514) 340-8260 ext. 25284
Email address: 
anne.gatignol [at] mcgill.ca
Current research: 

HIV

Projects: 

1. Using »ÆÆ¬ÀóÖ¦ÊÓÆµ-based technologies to target HIV »ÆÆ¬ÀóÖ¦ÊÓÆµ and »ÆÆ¬ÀóÖ¦ÊÓÆµ coding for cellular factors involved in HIV replication. The objective is to control viral replication for a use in gene therapy of HIV infection.
2. Elucidating HIV-induced modifications of the »ÆÆ¬ÀóÖ¦ÊÓÆµ interference (»ÆÆ¬ÀóÖ¦ÊÓÆµi) pathway during viral replication. The objective is to analyze the changes in proteins of the »ÆÆ¬ÀóÖ¦ÊÓÆµi pathway and in micro»ÆÆ¬ÀóÖ¦ÊÓÆµ expression to explain HIV-associated pathologies.
3. Analyzing virus-host molecular interactions in the regulation of the innate cell response to HIV infection in lymphocytes, monocytes and astrocytes in relationship with viral persistence in HIV-infected patients.
4. Function of TRBP-Dicer-Ago2 interactions in »ÆÆ¬ÀóÖ¦ÊÓÆµ interference and cellular localization in mammalian cells.

Selected publications: 

Research areas: 
Immunology
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