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UID:20250927T093512EDT-4962lsIcsS@132.216.98.100
DTSTAMP:20250927T133512Z
DESCRIPTION:\nRegistration coming soon.\n\nHost: Boris Bernhardt\n\n\nChart
 ing Cortical Axes of Plasticity and Environmental Sensitivity: From Animal
  Critical Periods to Human Development\n\nAbstract: The human cerebral cor
 tex exhibits a multi-decade maturational time course during which it retai
 ns an innate capacity for environment-driven plasticity. Elucidating how p
 lasticity is refined in the cortex over time is foundational to understand
 ing when the youth brain will be most vulnerable to negative environments—
 as well as most amenable to positive environments capable of supporting he
 althy development and fostering resiliency. Yet\, it remains unclear preci
 sely how plasticity unfolds in the child and adolescent brain\, in part du
 e to the challenge of studying developmental plasticity in vivo. In this t
 alk\, I will describe how multi-modal MRI can be harnessed to study functi
 onal and neurobiological hallmarks of critical period plasticity that have
  been identified in animal research\, including age-related changes in int
 rinsic activity\, thalamocortical connectivity\, and intracortical myelina
 tion. I will then demonstrate that developmental refinements in imaging co
 rrelates of critical period neurobiology progress along a sensorimotor-to-
 association axis across cortical regions and a deep-to-superficial axis ac
 ross cortical layers. Next\, I will provide evidence that the organization
  of developmental plasticity along these cortical axes influences when and
  where socioeconomic environmental influences become embedded in the brain
 . The talk will conclude by considering how progress in studying developme
 ntal plasticity may help to inform the type and timing of environmental en
 richment interventions for youth at risk for psychopathology.\n\nValerie S
 ydnor\n\nPostdoc\, University of Pittsburgh\n\n\n\nValerie Sydnor is a pos
 tdoctoral scholar at the University of Pittsburgh working in the Laborator
 y of Neurocognitive Development with Beatriz Luna. Valerie completed her u
 ndergraduate degree in Health and Human Biology at Brown University and re
 ceived her PhD in Neuroscience from the University of Pennsylvania. Her re
 search program investigates when during development different areas of the
  human cortex are most plastic—and therefore most sensitive to environment
 al exposures that confer either vulnerability or resiliency to psychopatho
 logy. Thus far in her research career\, Valerie has published 48 peer-revi
 ewed articles (13 first-author) and received continuous external funding t
 o support her work over an 8-year period. Outside of the lab\, Valerie is 
 an avid runner as well as an avid consumer of fantasy novels\, sunshine\, 
 and donuts.\n
DTSTART:20251016T200000Z
DTEND:20251016T210000Z
LOCATION:de Grandpré Communications Centre\, The Neuro
SUMMARY:Special BIC Lecture: Charting Cortical Axes of Plasticity and Envir
 onmental Sensitivity: From Animal Critical Periods to Human Development
URL:/infect-diseases/channels/event/special-bic-lectur
 e-charting-cortical-axes-plasticity-and-environmental-sensitivity-animal-c
 ritical-367977
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