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D2R awards $400K to translate »ÆÆ¬ÀóÖ¦ÊÓÆµ research into real-world solutions

Montreal, June 25, 2025 – The DNA to »ÆÆ¬ÀóÖ¦ÊÓÆµ Initiative (D2R) at »ÆÆ¬ÀóÖ¦ÊÓÆµ has awarded $400,000 to four projects that aim to bring »ÆÆ¬ÀóÖ¦ÊÓÆµ-based innovations closer to clinical and commercial reality, including vaccines and therapies for rare and infectious diseases.

D2R’s commercialization programs seek to bridge research and real-world impact by funding early validation and industry collaborations. The Commercialization Priming program, in partnership with Genome Quebec, supports early testing of promising ideas, while the Major Partnerships program helps researchers collaborate with industry to advance technologies toward market readiness.

The following projects and their principal investigators have been awarded funding:

Major Partnerships awards

  • Machine learning models for the design of »ÆÆ¬ÀóÖ¦ÊÓÆµ therapeutics: Development of experimental data,ÌýNicolas Moitessier (»ÆÆ¬ÀóÖ¦ÊÓÆµ)

In partnership with Deep Genomics, this project aims to speed up the discovery of »ÆÆ¬ÀóÖ¦ÊÓÆµ-based medicines using artificial intelligence. By combining lab-generated data with computational models, the team will lay the foundation for machine learning tools that could transform how »ÆÆ¬ÀóÖ¦ÊÓÆµ therapies are developed.

  • Rapid Antigen Discovery, m»ÆÆ¬ÀóÖ¦ÊÓÆµ Vaccine Delivery & Assessment Platform,ÌýJörg Fritz (»ÆÆ¬ÀóÖ¦ÊÓÆµ)

Announced at BIO International 2025, this project, co-funded by Médicament Québec, »ÆÆ¬ÀóÖ¦ÊÓÆµ Technologies and Therapeutics Inc., AReNA, NovoArc GmbH and the Victor Phillip Dahdaleh Institute, represents a major collaborative effort in the development of next-generation m»ÆÆ¬ÀóÖ¦ÊÓÆµ vaccines. The project will build a rapid preclinical platform to identify vaccine targets and test new m»ÆÆ¬ÀóÖ¦ÊÓÆµ vaccine technologies, enabling researchers to respond faster and more effectively to emerging infectious diseases. The project involves collaborations with academic and industry partners to validate the platform’s utility in real-world scenarios.

Commercialization Priming awards (in partnership with Genome Quebec)

  • Collaboration with QurCan Therapeutics to develop an »ÆÆ¬ÀóÖ¦ÊÓÆµ therapy to treat a genetic brain disease -ÌýGentil Benoit (»ÆÆ¬ÀóÖ¦ÊÓÆµ)

Researchers at »ÆÆ¬ÀóÖ¦ÊÓÆµ are collaborating with QurCan Therapeutics to develop a new »ÆÆ¬ÀóÖ¦ÊÓÆµ-based treatment for a rare neurodegenerative disorder. This project utilizes nanoparticles developed by QurCan Therapeutics that are designed to cross the blood-brain barrier.

  • Poly-NS sa»ÆÆ¬ÀóÖ¦ÊÓÆµ dengue vaccine: A novel platform for T cell-driven protection against severe dengue,ÌýSilvia Vidal (»ÆÆ¬ÀóÖ¦ÊÓÆµ)

In collaboration with researchers from Vaccines for Communities (V4C) and the Institut Pasteur, this project will adapt V4C's »ÆÆ¬ÀóÖ¦ÊÓÆµ dengue vaccine antigen to a self-amplifying »ÆÆ¬ÀóÖ¦ÊÓÆµ (sa»ÆÆ¬ÀóÖ¦ÊÓÆµ) platform. The team will conduct preclinical testing of the sa»ÆÆ¬ÀóÖ¦ÊÓÆµ-based candidate while also advancing the platform for broader applications in next-generation vaccine development.

These awards reflect D2R’s commitment to advancing »ÆÆ¬ÀóÖ¦ÊÓÆµ science from the lab to the clinic, and to building strong partnerships that accelerate innovation.

For more information on these projects, please visit D2R’s funded projects page.

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