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Mathieu Quesnel-Vallières

Academic title(s): 

Assistant Professor

Mathieu Quesnel-Vallières
Branch: 
Université de Sherbrooke
Department: 
Immunologie et biologie cellulaire
Areas of expertise: 
  • »ÆÆ¬ÀóÖ¦ÊÓÆµ splicing
  • Transcriptomics
  • Immunotherapy
  • Cancer Biology
  • Personalized Medicine
Biography: 

Mathieu's research has always focused on the link between »ÆÆ¬ÀóÖ¦ÊÓÆµ and disease. He first completed a Master's degree working on the evolution of HIV-1 and HCV, two »ÆÆ¬ÀóÖ¦ÊÓÆµ viruses, in Prof. Hugo Soudeyns' lab at CHU Sainte-Justine. He then completed a Ph.D. on the regulation of alternative »ÆÆ¬ÀóÖ¦ÊÓÆµ splicing in the laboratories of Prof. Benjamin Blencowe and Prof. Sabine Cordes at the University of Toronto. These studies established for the first time a causal link between »ÆÆ¬ÀóÖ¦ÊÓÆµ splicing defects and autism disorders. During his postdoctoral training with Prof. Kristen Lynch and Prof. Yoseph Barash at the University of Pennsylvania, he developed and applied bioinformatics tools for transcriptomic analyses to identify novel immunotherapy targets in cancer. His lab is now further pursuing this research to refine and expand the molecular profiling of therapeutic targets, and experimentally validate candidates.

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